follows suit and declares the outbreak to be a domestic public health emergency (PHE), remains to be seen. Given the growing number of cases and considering other factors, on July 23, 2022, the World Health Organization (WHO) declared the monkeypox outbreak to be a Public Health Emergency of International Concern (PHEIC), and provided a set of recommendations on actions that governments and others can take to address the outbreak. This number is likely a significant undercount due to a number of factors including: limited access to testing, particularly in the first few months of the outbreak lag time between seeing a provider and having a case confirmed knowledge gaps among providers and stigma that may make individuals reluctant to seek medical care, especially when sores are in the genital or anal region and transmission may be associated with same-sex sexual encounters. As of July 26, 3,591 cases in 46 states, Puerto Rico, and Washington, D.C., have been diagnosed (see Figure 1) this represents 19% of 19,188 confirmed global cases. In the U.S., the first monkeypox case in the current outbreak was identified on May 18, 2022. (See Box 1 for an overview of monkeypox illness, transmission and testing, prevention, and treatment.) and globally and marks the first time substantial local transmission has been reported in non-endemic countries across multiple continents. This current outbreak is the largest ever in the U.S. However, in May 2022, multiple cases were identified in several countries where monkeypox has not been endemic, including the United States (U.S.). The first human case was identified in 1970, and historically, it has primarily been found on the African continent, except in cases related to travel or imported animals.
Monkeypox is an infectious disease caused by the monkeypox virus, in the Orthopoxvirus genus, and is related to smallpox.
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